. 2014 Jan 27;52(2):129–136. doi: 10.2486/indhealth.ih-2013-0112

Table 4. Stepwise multiple regression analysis for serum cytokines.

Variables		B^†	SE	β	p-values
Dependents	Independents	B^†	SE	β	p-values
Log TNF-α (pg/ml)	Constant	−0.276	0.205		0.183
	Log IL-8	0.485	0.173	0.295	0.006

	adjusted R²	0.076
	F	7.887 (p = 0.006)

Log IL-8 (pg/ml)	Constant	1.105	0.128		0.000
	Log TNF-α	0.179	0.058	0.295	0.003
	TGF-β1	0.002	0.001	0.339	0.001
	BMI	−0.011	0.005	−0.240	0.014
	ILO category	0.048	0.024	0.191	0.050

	adjusted R²	0.235
	F	7.455 (p<0.001)

TGF-β1 (ng/ml)	Constant	−129.544	70.618		0.000
	Progression of CWP	12.264	4.961	0.247	0.016
	Log MCP-1	30.060	11.920	0.252	0.014
	%FEV₁/FVC ratio	2.238	0.969	0.229	0.023

	adjusted R²	0.178
	F	7.069 (p<0.001)

Log MCP-1 (pg/ml)	Constant	1.300	0.069		0.000
	TGF-β1	0.002	0.001	0.259	0.014
	Smoking status	0.084	0.036	0.242	0.022

	adjusted R²	0.124
	F	6.955 (p = 0.002)

^† Subjects: CWP patients with or without progression (n=85). B, regression coefficients; SE, standard error; β, standardized B. Independent variables: age, BMI, exposure period, smoking status (yes/no), ILO category of CWP, progression of CWP (yes/no), %FVC predicted, %FEV1 predicted, %FEV₁/FVC ratio, and measured serum cytokines.