Table 3.
Examples of glycosyltransferase families (CAZy).
| GT family | Mechanism | Fold | Glycosyltransferases | Known structures |
|---|---|---|---|---|
| 2 | I | GT-A | WbbD, WbwC, WbiP, CgtB, WbgO, WfaP, WfgD, LgtA | 7 |
| 6 | R | GT-A | GTA, GTB, A3GALT, WbnI, BoGT56a, GTA-like (Hm) | 4 |
| 7 | I | GT-A | B4GALT | 4 |
| 8 | R | GT-A | LgtC | 5 |
| 10 | I | GT-B | α3/4FUT, FutA, FutB, FucTa, FUT3, FUT4-7, 9-11 | 1 |
| 11 | I | GT-B | α2FUT, α3FUT (Hh), WbwK, Wbsj, FutC | – |
| 13 | I | GT-A | GnT I, MGAT1 | 1 |
| 14 | I | GT-A | C2GnT1, IGnT, GCNT2 | 1 |
| 16 | I | ? | MGAT2 | – |
| 17 | I | ? | MGAT3 | – |
| 18 | I | ? | MGAT5 | – |
| 23 | I | GT-B | α6FUT8, NodZ | 2 |
| 25 | I | ? | LgtB | – |
| 26 | I | ? | WfeD | – |
| 27 | R | GT-A | GALNT | 3 |
| 29 | I | GT-A | Animal sialyl-T, ST3GAL, ST6GAL, ST6GALNAC, ST8SIA | 3 |
| 31 | I | GT-A | C1GALT, B3GALT5 | 1 |
| 32 | R | ? | CgtD, Lgt5, A4GALT | – |
| 38 | I | ? | Bacterial PST | – |
| 42 | I | GT-A | Bacterial Sialyl-T, CstI, CstII | 2 |
| 52 | I | GT-B | Bacterial Sialyl-T, NST, WbwA | 1 |
| 54 | I | ? | MGAT4 | – |
| 80 | I | GT-B | Bacterial Sialyl-T, Pm0188, α6Sialyl-T (Psp), PmST1, multifunctional | 4 |
Fold, expected overall fold; Hh, Helicobacter hepaticus; Hm, Helicobacter mustelae; I, Inverting mechanism; Psp, Photobacterium sp.; R, Retaining mechanism; -T, -transferase.