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. 2014 Mar 5;7(4):513–522. doi: 10.1016/j.tranon.2014.02.008

Figure 1.

Figure 1

Effect of simvastatin on the growth of FaDu xenografts treated with radiation (XRT) and cetuximab (C225). Mice received XRT (30 Gy), C225, or simvastatin as single treatments (A) or XRT (30 Gy) plus C225 or XRT (30 Gy) plus C225 plus simvastatin (B), as specified in the Materials and Methods section. Values are the means ± SE of five tumors per group (unless otherwise specified). P values were calculated by Mann-Whitney test. *P < .05 compared to nontreatment group in A or XRT + C225 without simvastatin group in B.