Figure 4.

Pseudoprogression in a 68-year-old woman with glioblastoma multiforme. A-D) Axial contrast-enhanced fat-saturated T1-weighted MR images show a large enhancing mass centered in the right thalamus prior to treatment (A), immediately postoperative (B), two months later with increased contrast enhancing tumor after temozolomide chemoradiotherapy (C), and one month later with decreased tumor enhancement (D). T2-weighted images (not shown) demonstrated peri-tumoral vasogenic edema that followed the same patterns as contrast enhancement.