Figure 6.

Nonenhancing tumor progression in a 74-year-old man with glioblastoma multiforme after bevacizumab therapy. A) Axial contrast-enhanced T1-weighted MR image shows a peripherally enhancing mass in the right medial frontal gyrus (arrow). B) Axial contrast-enhanced fat-saturated T1-weighted MR image shows a cavity after surgical resection. C) Axial contrast-enhanced fat-saturated T1-weighted MR image one year later after surgical resection does not show any enhancing lesion to suggest recurrence; however, (D) axial FLAIR MR imaging shows new high signal (arrows) in the right gyrus rectus (more inferior than the original tumor site) compatible with nonenhancing tumor.