Table 2. PolyI:C and saline group comparison results of different assays.
LINE1 | IAP | Mecp2 | |||||||
---|---|---|---|---|---|---|---|---|---|
|
Mean |
s.d. |
P-value |
Mean |
s.d. |
P-value |
Mean |
s.d. |
P-value |
Hypothalamus | |||||||||
0.696 | 0.006 | 0.265 | 0.067 | ||||||
PolyI:C | F 0.694 | 0.005 | 0.935 | 0.014 | F 0.290 | 0.037 | |||
0.019* | 0.002** | ||||||||
M 0.700 | 0.005 | M 0.148 | 0.042 | ||||||
F 0.005** | 0.47 | F 0.000*** | |||||||
0.701 | 0.007 | 0.346 | 0.059 | ||||||
M 0.885 | M 0.202 | ||||||||
Saline | F 0.702 | 0.007 | 0.931 | 0.012 | F 0.362 | 0.046 | |||
M 0.700 | 0.007 | M 0.266 | 0.068 | ||||||
Striatum | |||||||||
0.707 | 0.011 | 0.930 | 0.050 | 0.295 | 0.179 | ||||
PolyI:C | 0.29 | 0.85 | 0.37 | ||||||
Saline | 0.704 | 0.010 | 0.936 | 0.066 | 0.345 | 0.121 |
Abbreviations: F, Female; IAP, intracisternal A particle; LINE1, long interspersed elements; M, Male; Mecp2, Methyl CpG Binding Protein2.
Mean methylation of all the markers for each assay. *P<0.05, **P<0.005 and ***P<0.0005.