Table 1. Means and standard deviations (s.d.) of regional brain volumes (before correction for whole brain volume) in cm³.

	Full sample (N=125)		MDD onset status				Serotonin transporter genotype
	M	s.d.	MDD onset (n=26)		No MDD onset (n=73)		SS (n=29)		SL (n=59)		LL (n=37)
			M	s.d.	M	s.d.	M	s.d.	M	s.d.	M	s.d.
Left hippocampus	2.77	0.33	2.70	0.35	2.77	0.33	2.65	0.25	2.80	0.35	2.81	0.35
Right hippocampus	2.95	0.34	2.94	0.35	2.91	0.33	2.88	0.28	2.96	0.36	2.99	0.35
Left amygdala	1.89	0.26	1.86	0.25	1.89	0.25	1.89	0.23	1.89	0.28	1.88	0.26
Right amygdala	1.83	0.28	1.75	0.24	1.85	0.29	1.85	0.27	1.85	0.26	1.80	0.31
Left medial OFC	7.55	1.80	7.13	1.47	7.62	2.00	6.96	1.78	7.58	1.60	7.94	2.05
Right medial OFC	7.19	1.71	6.80	1.27	7.27	1.87	6.62	1.92	7.16	1.54	7.66	1.70
Left lateral OFC	12.41	3.04	11.81	3.31	12.63	3.06	12.00	3.83	12.70	2.46	12.26	3.25
Right lateral OFC	13.33	2.75	13.00	2.63	13.50	2.92	13.11	3.07	13.57	2.33	13.11	3.16
Left limbic ACC	4.98	1.68	5.44	1.38	4.77	1.68	4.55	1.55	5.02	1.67	5.27	1.79
Right limbic ACC	5.77	1.91	5.51	1.99	5.99	1.87	5.98	1.79	5.60	2.01	5.88	1.88
Left paralimbic ACC	5.33	1.99	4.73	1.72	5.47	2.14	5.57	2.23	5.22	2.01	5.33	1.77
Right paralimbic ACC	4.79	1.80	4.79	1.55	4.67	1.89	4.67	2.02	4.91	1.82	4.67	1.63

Abbreviations: ACC, anterior cingulate cortex; MDD, major depressive disorder; OFC, orbitofrontal cortex.