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Effects of HO-1 on cell proliferation. Increased proliferation is shown by a+, decreased proliferation by a −, based on existing literature. In the developing lung exposed to hyperoxia, the net effect of HO-1 on the different cell lineages prevents the phenotypic changes of BPD. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars
