Table 2.
Correlation between IGFBP-1 expression and the clinicopathological features of the patients
| Clinicopathological Variables | IGFBP1 expression | P value | |
|---|---|---|---|
|
| |||
| High expression | Low expression | ||
| Gender | |||
| Male | 48 | 29 | >0.05 |
| Female | 9 | 4 | |
| Age | |||
| <45 | 25 | 12 | >0.05 |
| ≥45 | 32 | 21 | |
| Tumor number | |||
| Single | 49 | 23 | >0.05 |
| Multiple | 8 | 10 | |
| Maximal tumor size | |||
| ≤5 cm | 27 | 11 | >0.05 |
| >5 cm | 30 | 22 | |
| Tumor differentiation | |||
| I-II | 39 | 15 | <0.05 |
| III-IV | 18 | 18 | |
| Liver cirrhosis | |||
| No | 30 | 25 | <0.05 |
| Yes | 27 | 8 | |
| Serum AFP | |||
| ≤400 (ng/ml) | 16 | 8 | >0.05 |
| >400 (ng/ml) | 41 | 25 | |
| HBsAg status | >0.05 | ||
| Negative | 8 | 5 | |
| Positive | 49 | 28 | |
| Microvascular invasion or metastasis | |||
| No | 53 | 24 | <0.05 |
| Yes | 4 | 9 | |
| TNM stage | |||
| I-II | 36 | 6 | <0.001 |
| III | 21 | 27 | |