Table 3.

Association between four-protein signature risk and clinical pathological parameters in ESCC

Clinical parameters	Four-protein signature		r, P *
	Low risk	High risk
Age (years)
<58	60	15	0.128, 0.139
≥58	53	24
Gender
Male	84	30	-0.026, 0.832
Female	29	9
Differentiation
G1	33	11	0.073, 0.358
G2	72	21
G3	8	7
Invasive depth
T2	7	1	0.51, 0.626
T3	105	38
T4	1	0
LN metastasis
N0	65	12	0.234, 0.005
N1	48	27
pTNM stage
I/II	65	12	0.265, 0.001
III/IV	48	27

Kendall’s tau-b test;

^* p value <0.05 was considered significant.

LN: lymph node.