Table 3.
Univariate analysis and multivariate analyses of prognostic factors for overall survival in NSCLC patients
| Variable | Category | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| LOX | Positive/negative | 1.890 | 1.101-3.244 | 0.021 | 1.886 | 1.066-3.337 | 0.029 |
| Age | >65 years/≤65 years | 1.112 | 0.622-1.988 | 0.719 | 1.211 | 0.642-2.282 | 0.555 |
| Gender | Female/male | 0.784 | 0.454-1.355 | 0.383 | 0.767 | 0.405-1.454 | 0.416 |
| Pathological type | ADC/SCC | 1.337 | 0.772-2.313 | 0.300 | 1.252 | 0.698-2.247 | 0.451 |
| Differentiation | Moderate + Poor/well | 1.251 | 0.736-2.128 | 0.409 | 1.682 | 0.876-3.230 | 0.118 |
| Tumor size | >3 cm/≤3 cm | 1.380 | 0.825-2.307 | 0.220 | 1.166 | 0.670-2.028 | 0.587 |
| Lymph node involvement | Yes/No | 2.422 | 1.442-4.065 | 0.001 | 2.609 | 1.488-4.574 | 0.001 |
| TNM stage | II+III/I | 1.958 | 1.160-3.303 | 0.012 | 2.783 | 1.570-4.932 | < 0.001 |
HR: hazard ratio; ADC: Adenocarcinoma; SCC: Squamous cell cancer.