Table 1.

Association of miR-335 with clinicopathological characteristics of ESCC patients

Parameters	Group	Total	MiR-335 expression		P value
			Low	High
Gender	Male	54	39	15	0.731
	Female	13	10	3
Age (years)	< 60	40	30	10	0.675
	≥ 60	27	19	8
Tumor size (cm)	< 4 cm	46	34	12	0.831
	≥ 4 cm	21	15	6
Histological grade	G1	28	15	13	0.003
	G2+G3	39	33	5
Tumor stage	T1-T2	20	10	10	0.005
	T3-T4	47	39	8
Lymph nodes metastasis	Absence	39	23	16	0.002
	Presence	28	26	2
Clinical stage	I-II	41	24	17	0.001
	III-IV	26	25	1
Tumor location	Upper	6	5	1	0.555
	Middle	44	32	12
	Lower	17	12	5