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. 1996 Jul 1;16(13):4231–4239. doi: 10.1523/JNEUROSCI.16-13-04231.1996

Fig. 4.

Fig. 4.

A, B, NMDA receptor antagonists inhibit dopamine-induced IEG expression in rat primary striatal cultures. Northern blots from rat primary striatal culture probed with c-fos. A, Cultures were treated for 30 min with dopamine (50 μm). Pretreatment for 4 hr with MK-801 (1 μm) blockedc-fos induction; n = 4. B, Cultures were treated for 30 min with either dopamine (50 μm), SKF 38393 (50 μm), or SKF 82958 (50 μm). Pretreatment for 30 min with MK-801 (50 μm) or APV (100 μm) prevented c-fos induction;n = 8.