Fig. 11.
Transfected pENKAT12 and3xCRE-luciferase constructs are induced by forskolin in primary striatal cultures. MK 801 blocks this induction.A, Transfection with pENKAT12. B, Transfection with 3xCRE-luciferase. Transfected cells were treated with MK 801 (1 μm), forskolin (10 μm; FOR), or both, and CAT activity (pENKAT12) or luciferase activity (3xCRE-luc) were measured. Bars present the average fold induction ± SEM over baseline activity.Asterisks indicate statistically significant difference with forskolin treatment. Five experiments performed in triplicate were averaged.