Table 2. Multivariable RRs (95% CIs) for talc use and risk of ovarian cancer.

	Cases	controls	RR	(95% CI)a
Talc use
No b	363	469	1.00
Yes	242	219	1.48	1.15-1.91
Yes, non-perineal area c	112	103	1.43	1.03-1.98
Yes, perineal area	130	116	1.53	1.13-2.09
Frequency & duration of talc use
No	363	469	1.00
1 <=20 yrs & <=10 times/month	35	31	1.36	0.79-2.32
1 <=20 yrs & >10- <=30 times/month	23	30	1.16	0.63-2.12
1 <=20 yrs & >30 times/month	21	21	1.23	0.63-2.41
>20 yrs & <=10 times/month	45	49	1.27	0.80-2.01
>20 yrs & >10- <=30 times/month	51	43	1.57	0.99-2.50
>20 yrs & >30 times/month	67	45	2.08	1.34-3.23
P (6 df)				P=0.032
Total times of talc use
No	363	469	1.00
<=5200	49	52	1.20	0.77-1.88
>5200 to <=15600	46	47	1.38	0.87-2.20
>15,600 to <=52000	63	61	1.34	0.89-2.02
>52000	84	59	1.99	1.34-2.96
P (1 df)				P=0.0004
Total times of talc use
No	363	469	1.00
Before 1975
<=5200	24	35	0.84	0.47-1.51
>5200 to <=15600	29	29	1.41	0.79-2.53
>15,600 to <=52000	49	45	1.45	0.91-2.31
>52000	82	58	1.93	1.29-2.88
After 1975
<=5200	25	17	1.95	0.98-3.89
>5200 to <=15600	17	18	1.17	0.55-2.48
>15,600	16	17	0.98	0.45-2.13

^aAdjusted for race/ethnicity, age, education, tubal ligation, family history of breast/ovarian cancer, menopausal status, use of oral contraceptives and parity

^bSubjects (13 cases, 11 controls) reported tubal ligation and/or hysterectomy before started talc use and were included with the never users.

^cIncluded arms and extremities.