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. 2014 Sep 25;27(10):1787–1795. doi: 10.1021/tx500239q

Table 1. Half-Lifea of ECH in Rat and Mouse Blood or Plasma.

    half-life (min)
matrix concentration (μM) on ice 37 °C
rat plasma 1 347 53
rat plasma 80 693 50
rat blood 1 129 19.9
rat blood 80 305 24.6
mouse blood 1 NDb 44.9
mouse blood 80 ND 42.7
a

Half-life was determined from semi log plots of ECH concentration vs time curve using the equations y = a e–kx, and half-life = 0.693/k.

b

ND, not determined.