Table 5. Best responses to combined bortezomib/hydroxychloroquine, by prior response to bortezomib, including all subjects evaluable for response.
VGPR | PR | MR | SD | PD | ≥ PR | ≥ MR | ||
---|---|---|---|---|---|---|---|---|
Bortezomib naïve | 3 | 4 | 1 | 38% | 38% | |||
Bortezomib responsive | 1 | 2 | 1 | 0 | 25% | |||
Bortezomib refractory | 2 | 4 | 4 | 0 | 20% |
PD, progressive disease; VGPR, very good partial response; PR, partial response; MR, minor response; SD, stable disease