Table 1. Monoclonal antibodies used for cancer therapy able to induce, so far, hypersensitivity-associated acute coronary syndromes (ACS) of Kounis type (KS).
Generic name | Trade name | Coronary syndrome-induced |
---|---|---|
-ximabs | ||
Rituximab | Rituxan®, MabThera® | type II of KS6,7 |
Cetuximab | Erbitux® | type I of KS10 |
Brentuximab | Adcetris® | none, so far |
-zumabs | ||
Alemtuzumab | Campath-1H® | type I of KS11 |
Bevacizumab | Avastin® | ACS12–14 |
Trastuzumab | Herceptin® | ACS15,16 |
Ranibizumab | Lucentis® | ACS14 |
Pertuzumab | Perjeta® | none, so far |
Trastuzumab | Kadcyla™ | none, so far |
-umabs | ||
Denosumab | Prolia® Xgeva® | none, so far |
Ipilimumab | Yervoy® | none, so far |
Ofatumumab | Arzerra® | none, so far |
Panitumumab | Vectibix® | none, so far |
-omabs | ||
Catumaxomab | Removab® | none, so far |
Ibritumomab | Zevalin® | none, so far |
Tositumomab-131I | Bexxar® | none, so far |