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. 2014 Oct 20;9(10):e109281. doi: 10.1371/journal.pone.0109281

Table 1. Baseline Characteristics of 309 Patients.

Variables Group 1*(n = 43) Group 2*(n = 183) Group 3*(n = 75) Group 4*(n = 8) p-value
Age (yrs) 67.7±9.5a 67.5±10.5a 72.6±11.1b 71.1±14.5a 0.005
Male gender (%) 69.8% (30) 82% (150) 69.3% (52) 87.5% (7) 0.077
Body mass index (kg/m2) 25.4±3.6 24.8±3.6 25.0±4.1 24.9±3.5 0.850
Current smoking (%) 30.3% (13) 35.5% (65) 34.7% (26) 62.5% (5) 0.378
Diabetes mellitus (%) 51.2% (22) 46.4% (85) 42.7% (32) 75% (6) 0.333
Hypertension (%) 25.6% (11)a 18% (33)a 21.3% (16)a 50% (4)b 0.032
Total Cholesterol (mg/dL) 156.9±53.6 162.9±48.7 161.8±39.4 147.3±30.5 0.732
LDL (mg/dL) 91.6±40.9 90.1±41.7 96.2±35.9 85.3±23.1 0.699
HDL (mg/dL) 48.0±16.7 45.9±16.5 44.7±13.7 43.8±13.5 0.724
Old myocardial infarction (%) 74.4% (32) 71% (130) 68% (51) 87.5% (7) 0.652
Previous CABG (%) 0% (0) 4.4% (8) 2.7% (2) 0% (0) 0.310
Previous PCI for LM (%) 11.6% (5) 11.5% (21) 2.7% (2) 0% (0) 0.104
History of COPD (%) 11.6% (5) 5.5% (10) 14.7% (11) 0% (0) 0.066
Symptomatic PAOD (%) 7% (3)a 4.4% (8)a 14.7% (11)b 12.5% (1)b 0.037
Old stroke (%) 7% (3) 11.5% (21) 20% (15) 12.5% (1) 0.170
ARB/ACEI (%) 48.8% (21) 48.1% (88) 36% (27) 37.5% (3) 0.308
Statin use (%) 51.2% (22)a 48.1% (88)a 30.7% (23)b 25% (2)b 0.033
Ac sugar (mg/dL) 101.8±44.0a 112.4±56.7a 135.5±85.1b 106.1±22.9a 0.018
HBA1C (%) 5.50±2.61 6.36±2.02 6.40±2.11 5.93±0.61 0.092
ESRD (%) 0% (0)a 8.7% (16)b 25.3% (19)b 0% (0)a,b <0.001
Creatinine level (mg/dL) 1.02±0.34a 1.92±2.60a 3.42±3.36b 1.86±2.23a <0.001
White blood cell count 7.2±2.6a 7.7±3.8a 9.7±3.4b 9.8±2.9b <0.001
Troponin-I (ng/mL) 0.3±0.9a 2.09±1.18a 45.3±183.1b 16.7±40.3b 0.001
CK-MB (unit/L) 0.2±0.7a 0.39±2.3a 13.3±59.1b 7.43±20.6b 0.004
Troponin-I (after PCI) (ng/mL) 15.2±29.9a 15.2±40.6a 44.6±90.3b 44.1±60.2b <0.001
CK-MB (after PCI) (unit/L) 3.16±7.13a 3.72±11.72a 18.9±37.4b 17.9±23.9b <0.001

Data are expressed as % (n) or mean ± SD.

*Group 1 = angina pectoris, Group 2 = unstable angina, Group 3 = non ST-segment elevation myocardial infarction, Group 4 = post-ST-segment elevation myocardial infarction angina.

LDL = Low-density lipoprotein; HLD = high-density lipoprotein; CABG = coronary artery bypass surgery; LM = left main; PCI = percutaneous coronary intervention; COPD = chronic obstructive lung disease; PAOD = peripheral arterial obstructive disease; ARB/ACEI = angiotensin II type I receptor blcoker/angiotensin converting enzyme inhibitor; HBA1C = hemoglobin A1C; ESRD = end-stage renal disease; CK = Creatine phosphokinase.

indicated measurement upon presentation.

indicated therapy ≥5 week prior to be recorded.

Letters (a,b) indicate significant difference (at 0.05 level) by Bonferroni multiple-comparison post hoc test.