Table 4. Gominer Analysis based for over-expressed genes in CF signature versus HC.
| GO ID | GO category | Number of significant genes | Enrichment | FDR |
| A. | Cluster D - CF signature | |||
| GO:0008104 | protein localization | 73 | 1.74 | 0.00 |
| GO:0033036 | macromolecule localization | 82 | 1.63 | 0.00 |
| GO:0045184 | establishment of protein localization | 63 | 1.73 | 0.01 |
| GO:0016050 | vesicle organization | 12 | 4.46 | 0.01 |
| GO:0015031 | protein transport | 62 | 1.73 | 0.00 |
| GO:0006464 | protein modification process | 97 | 1.49 | 0.01 |
| GO:0046907 | intracellular transport | 56 | 1.75 | 0.01 |
| GO:0051641 | cellular localization | 77 | 1.57 | 0.01 |
| GO:0034613 | cellular protein localization | 41 | 1.94 | 0.01 |
| GO:0070727 | cellular macromolecule localization | 41 | 1.93 | 0.01 |
| GO:0043412 | macromolecule modification | 99 | 1.45 | 0.01 |
| GO:0016192 | vesicle-mediated transport | 49 | 1.78 | 0.01 |
| GO:0044260 | cellular macromolecule metabolic process | 242 | 1.19 | 0.01 |
| GO:0006886 | intracellular protein transport | 35 | 1.92 | 0.01 |
| B. | Cluster E - CF signature | |||
| GO:0009611 | response to wounding | 54 | 2.48 | 0.00 |
| GO:0006952 | defense response | 53 | 2.45 | 0.00 |
| GO:0023052 | signaling | 148 | 1.54 | 0.00 |
| GO:0023033 | signaling pathway | 121 | 1.63 | 0.00 |
| GO:0023046 | signaling process | 112 | 1.60 | 0.00 |
| GO:0023060 | signal transmission | 111 | 1.58 | 0.00 |
| GO:0007165 | signal transduction | 101 | 1.62 | 0.00 |
| GO:0006955 | immune response | 51 | 2.13 | 0.00 |
| GO:0002376 | immune system process | 70 | 1.84 | 0.00 |
| GO:0048583 | regulation of response to stimulus | 47 | 2.17 | 0.00 |
| GO:0035466 | regulation of signaling pathway | 60 | 1.94 | 0.00 |
| GO:0035556 | intracellular signal transduction | 73 | 1.78 | 0.00 |
| GO:0007243 | intracellular protein kinase cascade | 41 | 2.28 | 0.00 |
| GO:0023014 | signal transmission via phosphorylation event | 41 | 2.28 | 0.00 |
| GO:0006954 | inflammatory response | 27 | 2.85 | 0.00 |
| GO:0002263 | cell activation involved in immune response | 14 | 4.78 | 0.00 |
| GO:0002366 | leukocyte activation involved in immune response | 14 | 4.78 | 0.00 |
| GO:0006950 | response to stress | 100 | 1.57 | 0.00 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 36 | 2.37 | 0.00 |
| GO:0007166 | cell surface receptor linked signaling pathway | 74 | 1.73 | 0.00 |
| GO:0023034 | intracellular signaling pathway | 80 | 1.65 | 0.00 |
| GO:0050817 | coagulation | 28 | 2.61 | 0.00 |
Only GO categories enriched in cluster D (A) and in cluster E (B) with FDR less than 1%, with enrichment superior to 2 and with more than 10 genes are displayed.