Table 1. Descriptive results (n = 93).
| Early cUS; n (%) | ||
| Normal | 26 (28.0) | |
| Mild abnormalities | 55 (59.1) | |
| Moderate abnormalities | 3 (3.2) | |
| Severe abnormalities | 9 (9.7) | |
| Term cUS; n (%) $ | ||
| Ex-vacuo VM | 18 (19.4) | |
| Enlargement eCSF space | 41 (44.1) | |
| T1- and T2-weighted TEA-MRI; median (IQR; range) | ||
| Global brain abnormality score | 3 (2–6; 0–15) | |
| WM score | 3 (2–4; 0–11) | |
| Cortical GM score | 0 (0; 0–3) | |
| Deep GM score | 0 (0; 0–3) | |
| Cerebellum score | 0 (0–1; 0–7) | |
| Term DWI – ADC values *10 −3 mm2/s; median (IQR; range) Δ | ||
| Frontal WM | R | 1.611 (1.516–1.666; 1.292–1.840) |
| L | 1.626 (1.526–1.679; 1.324–1.837) | |
| Occipital WM | R | 1.579 (1.508–1.661; 1.367–1.794) |
| L | 1.607 (1.523–1.687; 1.356–1.843) | |
| Parieto-occipital WM | R | 1.654 (1.581–1.716; 1.409–1.843) |
| L | 1.662 (1.579–1.727; 1.434–1.870) | |
| Parietal WM | R | 1.610 (1.538–1.671; 1.382–1.923) |
| L | 1.600 (1.524–1.664; 1.408–1.906) | |
| Cerebellum | R | 1.075 (1.021–1.121;.920–1.242) |
| L | 1.078 (1.025–1.125;.911–1.271) | |
| Neurodevelopmental outcome (BSITD-III) at 24 months’ CA; median (IQR; range) | ||
| Cognitive composite score | 105 (95–110; 70–145) | |
| Cognitive scaled score | 11 (9–12; 4–19) | |
| Motor composite score | 107 (100–112; 73–142) | |
| Fine motor scaled score | 13 (11–14; 5–19) | |
| Gross motor scaled score | 9 (9–10; 6–15) | |
IQR: interquartile range; L: left hemisphere; R: right hemisphere;
$
term cUS data were missing for ten infants;
Δ
presented are ADC values uncorrected for PMA.