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. 2014 Jun 23;7:e29587. doi: 10.4161/cib.29587

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Copyright © 2014 Landes Bioscience

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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graphic file with name cib-7-e29587-g1.jpg — Figure 1. Schematic representation of membrane contact sites and their functions. Organelle dynamics indicates both the shape and motility of involved organelles. For LD and Pex, which are believed to originate from the ER, the role of direct contacts observed with this compartment remains unclear and may be implicated in lipid transfer between the ER and the mature form of the organelles.⁷⁸^,⁷⁹ ER, endoplasmic reticulum; Pex, peroxisomes; LD, lipid droplets; Mito, mitochondria; Melano, melanosomes; Golgi, Golgi apparatus; EE, early endosomes; LE, late endosomes; MVBs, multivesicular bodies; Lyso, lysosomes; ILV, intraluminal vesicles.