Table 3. Predictors of first CR.
Univariate model | Multivariate model | |||
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (per 10 years) | 0.99 (0.83–1.19) | 0.886 | 0.98 (0.79–1.23) | 0.759 |
Male (versus female) | 0.69 (0.46–1.04) | 0.075 | 0.77 (0.47–1.27) | 0.302 |
Systolic blood pressure (per 10 mmHg) | 1.00 (0.91–1.09) | 0.959 | 1.06 (0.96–1.17) | 0.276 |
Serum albumin (per 1.0 g/dL) | 0.86 (0.67–1.11) | 0.249 | 1.04 (0.74–1.45) | 0.818 |
Serum creatinine (per 1.0 mg/dL) | 0.47 (0.21–0.96) | 0.037 | 0.25 (0.03–1.68) | 0.163 |
Urinary protein excretion (per 1.0 g/day) | 1.01 (0.95–1.06) | 0.730 | 1.16 (0.29–4.18) | 0.823 |
ACE inhibitor or ARB therapy | 0.66 (0.44–1.02) | 0.061 | 0.56 (0.26–1.31) | 0.170 |
Immunosuppressive treatmentduring follow-up period | ||||
No immunosuppressive agents | Reference | Reference | ||
Prednisolone | 1.76 (1.00–2.96) | 0.048 | 1.78 (1.01–3.10) | 0.045 |
Prednisolone+cyclosporine | 2.18 (1.41–3.36) | <0.001 | 1.95 (1.16–3.26) | 0.011 |
NOTE: HR, hazard ratio; CI, confidence interval.
Data are the HR, 95% CI, and P-value from Cox proportional hazard regression analyses.
Adjusted for baseline characteristics (age, sex, systolic pressure, serum albumin level, serum creatinine level, urinary protein, use of immunosuppressive therapy).
Abbreviations: CR, complete remission; IMN, idiopathic membranous nephropathy.