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. 2014 Oct 20;9(10):e110376. doi: 10.1371/journal.pone.0110376

Table 3. Predictors of first CR.

Univariate model Multivariate model
HR (95% CI) P-value HR (95% CI) P-value
Age (per 10 years) 0.99 (0.83–1.19) 0.886 0.98 (0.79–1.23) 0.759
Male (versus female) 0.69 (0.46–1.04) 0.075 0.77 (0.47–1.27) 0.302
Systolic blood pressure (per 10 mmHg) 1.00 (0.91–1.09) 0.959 1.06 (0.96–1.17) 0.276
Serum albumin (per 1.0 g/dL) 0.86 (0.67–1.11) 0.249 1.04 (0.74–1.45) 0.818
Serum creatinine (per 1.0 mg/dL) 0.47 (0.21–0.96) 0.037 0.25 (0.03–1.68) 0.163
Urinary protein excretion (per 1.0 g/day) 1.01 (0.95–1.06) 0.730 1.16 (0.29–4.18) 0.823
ACE inhibitor or ARB therapy 0.66 (0.44–1.02) 0.061 0.56 (0.26–1.31) 0.170
Immunosuppressive treatmentduring follow-up period
No immunosuppressive agents Reference Reference
Prednisolone 1.76 (1.00–2.96) 0.048 1.78 (1.01–3.10) 0.045
Prednisolone+cyclosporine 2.18 (1.41–3.36) <0.001 1.95 (1.16–3.26) 0.011

NOTE: HR, hazard ratio; CI, confidence interval.

Data are the HR, 95% CI, and P-value from Cox proportional hazard regression analyses.

Adjusted for baseline characteristics (age, sex, systolic pressure, serum albumin level, serum creatinine level, urinary protein, use of immunosuppressive therapy).

Abbreviations: CR, complete remission; IMN, idiopathic membranous nephropathy.