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. 2014 Oct 20;9(10):e110376. doi: 10.1371/journal.pone.0110376

Table 4. Predictors of hospitalization due to infection (n = 171).

Univariate model Multivariate model
HR (95% CI) P-value HR (95% CI) P-value
Age (per 10 years) 3.07 (1.56–6.58) <0.001 3.11 (1.45–7.49) 0.003
Male (versus female) 1.49 (0.45–6.63) 0.533 1.34 (0.37–6.29) 0.666
Serum albumin (per 1.0 g/dL) 0.73 (0.33–1.50) 0.394 1.24 (0.47–3.21) 0.662
Serum creatinine (per 1.0 mg/dL) 5.27 (1.81–12.5) 0.004 2.62 (0.83–7.70) 0.098
Urinary protein excretion (per 1.0 g/day) 0.96 (0.79–1.12) 0.613 0.92 (0.71–1.13) 0.468
Immunosuppressive treatmentduring follow-up period
No immunosuppressive agents Reference Reference
Prednisolone 9.54 (1.54–182.6) 0.014 11.8 (1.59–242.5) 0.014
Prednisolone+cyclosporine 7.26 (1.29–135.8) 0.022 10.3 (1.59–204.4) 0.012

NOTE: HR, hazard ratio; CI, confidence interval.

Data are the HR, 95% CI, and P-value from Cox proportional hazard regression analyses.

Adjusted for baseline characteristics (age, sex, systolic pressure, serum albumin level, serum creatinine level, urinary protein, use of immunosuppressive therapy).

Abbreviations: IMN, idiopathic membranous nephropathy.