Table 5. Predictors of hospitalization due to infection in patients treated with immunosuppressive therapy.

	Univariate model		Multivariate model
	HR (95% CI)	P-value	HR (95% CI)	P-value
Age (per 10 years)	2.71 (1.42–5.55)	0.002	2.80 (1.20–7.83)	0.016
Male (versus female)	1.16 (0.34–5.21)	0.827	1.65 (0.39–8.46)	0.500
Serum albumin (per 1.0 g/dL)	1.12 (0.46–2.55)	0.792	2.15 (0.64–7.99)	0.217
Serum creatinine (per 1.0 mg/dL)	4.15 (1.42–9.53)	0.013	1.15 (0.31–3.88)	0.830
Urinary protein excretion (per 1.0 g/day)	0.92 (0.73–1.09)	0.374	0.94 (0.70–1.19)	0.633
Immunosuppressive treatment within 1 monthafter kidney biopsy
Prednisolone	Reference		Reference
Prednisolone+cyclosporine	1.45 (0.46–4.89)	0.524	3.22 (0.74–16.9)	0.119
Initial dose of PSL/mg/day	0.97 (0.92–1.01)	0.162	1.00 (0.94–1.07)	0.943
25% decrease of proteinuria within 1 monthafter initial immunosuppressive therapy	5.78 (1.67–26.4)	0.005	7.27 (1.74–37.7)	0.007

NOTE: HR, hazard ratio; CI, confidence interval.

Data are the HR, 95% CI, and P-value from Cox proportional hazard regression analyses.

This analysis is based on data from 100 patients because the decrease rate of proteinuria was missing for one patient.

Adjusted for baseline characteristics (age, sex, systolic/diastolic pressure, serum albumin level, serum creatinine level, urinary protein, use of immunosuppressive therapy, initial dose of PSL (mg)/day, 25% decrease of proteinuria within 1 month after initial immunosuppressive therapy).

Abbreviations: IMN, idiopathic membranous nephropathy.