Table 2. Characteristics of the urinary biomarkers.

	AUC (95% CI)	Cut-offvalue	Sensitivity(95% CI)	Specificity(95% CI)	Positivepredictive value	Negativepredictive value	Positivelikelihood ratio	Negativelikelihood ratio	P value
NGAL (ng/mgcreatinine)	0.876 (0.800–0.951)	61.0	0.78 (0.62–0.89)	0.86 (0.71–0.95)	0.83	0.74	5.57	0.26	<0.0001
MCP-1 (pg/mg creatinine)	0.781 (0.677–0.885)	642.0	0.75 (0.59–0.87)	0.78 (0.62–0.90)	0.79	0.69	3.41	0.32	<0.0001
L-FABP (ng/mg creatinine)	0.635 (0.509–0.762)	91.3	0.35 (0.21–0.52)	0.97 (0.86–1.00)	0.93	0.55	11.7	0.67	0.041
IL-18 (pg/mgcreatinine)	0.595 (0.463–0.726)	268.9	0.43 (0.27–0.59)	0.89 (0.75–0.97)	0.67	0.56	3.91	0.64	0.153
Osteopontin (µg/mg creatinine)	0.618 (0.491–0.745)	17.6	0.45 (0.29–0.62)	0.81 (0.65–0.92)	0.6	0.55	2.37	0.68	0.075
Cystatin C (ng/mg creatinine)	0.511 (0.379–0.643)	13.6	0.35 (0.21–0.51)	0.89 (0.75–0.97)	0.41	0.21	3.18	0.73	0.866
Clusterin (µg/mg creatinine)	0.521 (0.392–0.650)	1.63	0.65 (0.49–0.79)	0.49 (0.32–0.66)	0.50	0.46	1.27	0.71	0.746

Abbreviations: AUC, area under the curve; CI, confidence interval; IL-18, interleukin-18; L-FABP, liver-type fatty acid-binding protein; MCP-1, monocyte chemotactic protein-1; NGAL, neutrophil gelatinase-associated lipocalin.