Table 2. Main histological diagnoses in 56 native kidney biopsies from 51 patients carrying a diagnosis of sarcoidosis.
Diagnosis | N |
Granulomatous interstitial nephritis* | 19 |
Interstitial nephritis without granuloma | 8 |
Diabetic nephropathy | 7 |
Focal Segmental Glomerulosclerosis | 6 |
Chronic/Advanced sclerosing changes** | 6 |
Immune complex mediated glomerulonephritis | 3 |
Acute tubular injury | 3 |
Amyloid | 1 |
Membranous glomerulopathy | 1 |
Thin glomerular basement membrane disease | 1 |
Non specific changes | 1 |
*A diagnosis of granulomatous interstitial nephritis consistent with renal sarcoidosis was rendered when other potential differential diagnoses (drug reactions, bacterial, mycobacterial and fungal infections, de novo or recurrent Wegener’ granulomatosis, foreign body reaction) could be excluded.
**This category includes: Severe global glomerulosclerosis; Tubulointerstitial scarring; Hypertensive nephrosclerosis; Transplant glomerulopathy with tubulointerstitial scarring.