Table 3. The clinical characteristics and ocular surface parameters of enrolled subjects.
| Cch (n = 198) | DES & non-Cch (n = 86) | normal controls (n = 76) | P value | ||||
| OD | OS | OD | OS | OD | OS | ||
| Visual acuity | 0.55±0.21 | 0.51±0.24 | 0.58±0.24 | 0.57±0.23 | 0.55±0.27 | 0.54±0.23 | 0.886 |
| ST | <0.001 ‡ | ||||||
| <5 mm | 79 (39.9%) | 80 (40.4%) | 28 (32.6%) | 30 (34.9%) | 0 | 0 | Cch vs DES: 0.051 |
| 5–10 mm | 63 (31.8%) | 59 (29.8%) | 21 (24.4%) | 17 (19.8%) | 25 (32.9%) | 23 (30.3%) | Cch vs Con: <0.001 ‡ |
| >10 mm | 56 (28.3%) | 59 (29.8%) | 37 (43.0%) | 39 (45.3%) | 51 (67.1%) | 53 (69.7%) | DES vs Con: <0.001 ‡ |
| TBUT | <0.001 ‡ | ||||||
| <5 s | 95 (48.0%) | 92 (46.5%) | 28 (32.6%) | 28 (32.6%) | 0 | 1 (1.3%) | Cch vs DES: 0.001 † |
| 5–10 s | 82 (41.4%) | 84 (42.4%) | 33 (38.3%) | 35 (40.7%) | 29 (38.2%) | 29 (38.2%) | Cch vs Con: <0.001 ‡ |
| >10 s | 21 (10.6%) | 22 (11.1%) | 25 (29.1%) | 23 (26.7%) | 47 (61.8%) | 46 (60.5%) | DES vs Con: <0.001 ‡ |
| FS | 0.010 * | ||||||
| binocular positive | 3 (1.5%) | 1 (1.2%) | 0 | ||||
| monocular positive | 3 (1.5%) | 4 (4.7%) | 0 | ||||
| medium score | 1 | 1 | 1 | 1 | 0 | 0 | |
| IOP (mmHg) | 14.9±2.9 | 14.6±3.5 | 16.6±3.2 | 16.5±2.7 | 16.2±4.5 | 14.9±5.7 | 0.648 |
Con: normal controls.
*: P<0.05, †: P<0.01, ‡: P<0.001.