Table 4. The OSDI score, NEI VFQ-25 composite score, and the scores for each VFQ-25 subscale in enrolled subjects.
| Cch (n = 198) | DES & non-Cch (n = 86) | normal controls (n = 76) | P value | subgroup comparison | |
| OSDI | |||||
| average | 19.3±22.1 | 16.8±12.2 | 3.6±5.2 | <0.001‡ | Cch vs DES: 0.934, Cch vs Con: <0.001, DES vs Con: <0.001 |
| median | 12.5 | 15.9 | 0 | ||
| VFQ-25 | |||||
| General health | 56.3±14.6 | 56.2±15.2 | 62.5±15.7 | 0.012* | Cch vs DES: 0.998, Cch vs Con: 0.013, DES vs Con: 0.004 |
| General Vision | 65.9±13.1 | 68.2±13.7 | 69.8±12.7 | 0.096 | |
| Ocular Pain | 84.0±19.4 | 83.6±14.9 | 93.7±12.8 | 0.001† | Cch vs DES: 0.957, Cch vs Con: 0.001, DES vs Con: <0.001 |
| Near Activities | 81.6±17.4 | 89.1±16.1 | 87.9±14.1 | 0.001† | Cch vs DES: 0.003, Cch vs Con: 0.027, DES vs Con: 0.951 |
| Distance Activities | 91.1±14.6 | 94.4±12.3 | 96.3±8.9 | 0.116 | |
| Social Functioning | 93.1±13.5 | 95.9±11.9 | 97.7±8.2 | 0.202 | |
| Mental Health | 90.3±15.6 | 85.2±15.2 | 92.6±12.2 | 0.008† | Cch vs DES: 0.033, Cch vs Con: 0.878, DES vs Con: 0.011 |
| Role Difficulties | 88.2±21.1 | 91.6±15.5 | 93.7±16.0 | 0.096 | |
| Dependency | 93.6±15.7 | 94.4±12.6 | 96.3±13.9 | 0.462 | |
| Color Vision | 93.7±12.7 | 95.7±12.4 | 97.7±8.5 | 0.054 | |
| Peripheral Vision | 92.0±15.8 | 95.1±12.8 | 97.3±8.9 | 0.234 | |
| VFQ-25 composite score | 87.4±12.3 | 87.7±10.0 | 92.3±8.0 | 0.007† | Cch vs DES: 0.854, Cch vs Con: 0.004, DES vs Con: 0.011 |
OSDI: Ocular Surface Disease Index, NEI VFQ-25: 25-item National Eye Institute Visual Function Questionnaire, DES: dry eye syndrome, Cch: conjunctivochalasis, Con: normal controls.
*: P<0.05, †: P<0.01, ‡: P<0.001.