TABLE 1.

BIOLOGICAL PROPERTIES OF VIRAL VECTORS USED FOR GENE DELIVERY INTO CELLS IN THE TREATMENT OF VARIOUS DISEASES AND/OR SPORTS INJURIES [9, 14–16].

Viral vectors	Biological properties of vector
Adenoviruses	efficiency: average, infects only mitotic cells capacity: large durability of expression: high other features: cytotoxic/immunogenic in high doses,
Adeno-associated viruses (AAV)	efficiency: depends on the type of transfected cells capacity: small durability of expression: high other features: specifically cytotoxic/immunogenic; low efficiency of methods ofAAV obtaining
Herpesviruses (e.g., HSV-1)	efficiency: high, infects mitotic and postmitotic cells capacity: large durability of expression: high other features: cytotoxic/immunogenic in high doses
Oncoretroviruses, e.g., Rous sarcoma virus (RSV), Moloney murine leukaemia virus (MLV)	efficiency: infects mitotic cells capacity: small durability of expression: high other features: increased immune response; frequently causes insertional mutagenesis
Lentiviruses, e.g., simian immunodeficiency virus (SIV)	efficiency: high, does not require dividing cells capacity: large durability of expression: high other features: low cytotoxicity