Skip to main content
. 2014 Oct 20;9(10):e110972. doi: 10.1371/journal.pone.0110972

Table 1. Statistically significant mean gene expression differences between Aging and Development Periods (Multiple ANOVA results).

Reduced with Aging Increased with Aging
Gene Adjusted p-value Fold-Difference Gene Adjusted p-value Fold-Difference
CX3CL1 5.07E-21 −1.75 GFAP 4.33E-05 1.37
CX3CR1 8.00E-06 −2.00 TSPO 1.87E-03 1.23
BDNF 1.53E-05 −1.39 MOBP 2.77E-03 1.43
CD68 1.56E-04 −1.26 TRAF6 3.41E-03 1.17
CASP1 1.63E-04 −1.35 NFKB1 7.76E-03 1.11
AIF1 (IBA1) 1.63E-04 −1.31 TLR4 6.16E-02 1.12
PTGS2 (COX-2) 1.75E-04 −1.44 IL1R1 9.70E-02 1.21
PDGFA 1.34E-03 −1.14
DBN1 1.34E-03 −1.13
MYD88 1.34E-03 −1.24
NGF 1.34E-03 −1.14
SYP 2.11E-03 −1.18
IL1B 7.33E-03 −1.22
BACE1 5.33E-02 −1.11

Multiple ANOVA results, giving fold changes, showing that mean expression was significantly lower (left) or higher (right) in Aging compared with Development. A negative fold-change represents decreased expression in the Aging compared to Development group, and vice versa. Italicized p-values are nonsignificant after correction for multiple comparisons. In p-values, term E-number = ×10−number. (Development: n = 87; Aging: n = 144).