Expression of novel pancreatic genes in dissected guts of tadpole stage embryos. Gene expression patterns were revealed by whole mount in situ hybridization at three representative stages, stage 34–36, stage 40–41, and stage 42–43. These genes are expressed in the pancreatic rudiments of stage 34–36 embryos. The dorsal and ventral pancreatic buds are indicated with the black and white arrows, respectively and the liver bud is marked by an asterisk. A whole embryo was shown for HES3. While the Xenopus laevis gene designated here as HES3 (also known as Xenopus ESR2) has a best blastP match to human HES5, blastN to X. tropicalis and synteny relations identifies it as a gene distinct from tropicalis hes5 called hes3. Anterior to the left, dorsal to the top.