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. 2014 Oct 20;2:143. doi: 10.1186/s40478-014-0143-5

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© Tobin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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CAP decreases expression of pro-inflammatory cytokines in the brain following FPI. Multiplex analysis of cytokines in tissue from the ipsilateral cortex of C57BL/6 mice following FPI. Note the significant reductions in IL-13, IL-15, CCL2 (MCP1), and IL-10. The reduction of this subset of chemokines and cytokines is consistent with the reduction in cells capable of producing these inflammatory cytokines. Sham + vehicle (N = 4); sham + CAP (N = 4); FPI + vehicle (N = 4); FPI + CAP (N = 4). The symbol * indicates P < 0.05.