Table 2.
Change of circulating inflammatory and endothelial markers
| Control | RA | IBD | |
|---|---|---|---|
| CRP, μg/mL | 0.90 (9.50, 2.00) | 3.8 (0.7, 7.9)*** | 1.70 (0.70, 4.05)*# |
| IL-1β, pg/mL | 0.74 (0.31, 1.23) | 0.87 (0.36, 2.95)* | 0.71 (0.32, 1.81) |
| IL-6, pg/mL | 0.52 (0.33, 0.80) | 1.52 (0.54, 3.37)*** | 1.03 (0.56, 1.79)*** |
| IL-10, pg/mL | 11.4 (6.6, 18.6) | 15.8 (10.7, 38.7)* | 19.3 (12.5, 31.3)*** |
| TNF-α, pg/mL | 2.32 (1.46, 3.75) | 3.29 (1.99, 6.10)* | 3.27 (2.18, 4.22)** |
| MIF, ng/mL | 25.7 (21.4, 33.1) | 49.3 (39.5, 79.0)** | 46.2 (37.6, 58.2)** |
| vWF, μg/mL | 7.56 (5.25, 12.50) | 10.83 (7.68,19.36)** | 11.32 (7.75,18.15)** |
| E-selectin + EMP, (/μL) | 154 (122, 185) | 164 (129, 204) | 132(109, 184) |
Results were expressed as median (25, 75 percentile). *, **, *** vs. control (p < 0.05, <0.01, <0.001), # vs. RA (p < 0.05). CRP: C-reactive protein; EMP: endothelial microparticles; IBD: inflammatory bowel disease; IL-1β: interleukin-1β; IL-6: interleukin-6; IL-10: interleukin-10; MIF: macrophage migration inhibitory factor; RA: rheumatoid arthritis; TNF-α: tumour necrosis factor-α; vWF: von Willebrand factor.