Table 1. Quantification of BMEL-GFP cell participation in regeneration of Alb-uPA/SCID mouse livers.
| Percent repopulation
|
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|---|---|---|---|---|---|---|
| Chosen fields
|
Total section
|
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| Donor cells | Time in vivo, wk | GFP | H-2Kk | GFP | H-2Kk | Clusters per section |
| 9A1-GFP | 3 | 6.1 ± 2.3 | 2.1 ± 0.7 | 141 (18) | ||
| n = 9 | n = 5 | |||||
| 14B3-GFP | 3 | 1.7 ± 0.9 | 3.1 | 0.8 | 19 (2) | |
| n = 4 | n = 1 | |||||
| 9A1-GFP | 5 | 4.5 ± 5.2 | 5.3 | 0.8 | 8 (4) | |
| n = 4 | n = 1 | |||||
| 14B3-GFP | 5 | 6.0 ± 3.1 | 11.5 ± 3.1 | 2.0 | 68 (16) | |
| n = 6 | n = 3 | |||||
| 9A1-GFP | 8 | 4.7 ± 3.2 | 22.3 ± 3.7 | 1.6 | 4.5 | 15 (7) |
| n = 6 | n = 3 | |||||
| 14B3-GFP | 8 | 1.1 ± 1.0 | 0.3 | 7 (4) | ||
| n = 2 | ||||||
Total liver sections are the composite of ≈30 images through a ×2.5 objective. Although only one field is presented for five of the six livers, each represents 30 chosen fields. Results are presented as mean ± SD; n = number of fields analyzed. Numbers in parentheses represent the number of bile duct areas per liver section.