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. 2013 Mar 1;5(2):53–66. doi: 10.4161/isl.24785

Table 3. Advantages and disadvantages of a systemic immunomodulatory approach.

Advantages
▪ Due to general approach, efficacy increases
Disadvantages
▪ General immune suppression
▪ Systemic side effects
▪ Extrapolation dose, timing and frequency treatment administration