Table 1.

Public health operational research questions SCORE is currently pursuing or will soon ask

•	A better mapping tool than Kato-Katz stool exam for S. mansoni
•	A highly sensitive and specific diagnostic tool for use when approaching elimination of transmission
•	Best means of PZQ distribution to gain & sustain morbidity control by MDA
•	Best combination of interventions to eliminate S. haematobium and S. mansoni transmission
•	How can we improve and best deliver effective snail control
•	Better way to show impact of MDA on morbidity
•	Does MDA impact schistosome population structures—as clues to the development of drug resistance
•	Can snail data predict the effectiveness of MDA for a given village
•	Rapid Answer Projects—analyzing existing data for: “double treatment”; “hemastix efficacy post-treatment campaigns”; “reinfection of adults with S. haematobium”; “uses and impact of niclosamide”