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. 2004 May 20;101(22):8425–8430. doi: 10.1073/pnas.0400625101

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Fig. 4. — Body weight, lifespan, and behavioral testing. (a) The body weight in Hexb^-/-MIP-1α^-/- and Hexb^-/-MIP-1α^+/- mice was higher at and after 15 weeks of age compared with Hexb^-/-MIP-1α^+/+ mice. The data are means from three to five mice for each genotype and data point. (b) Survival of the Hexb^-/- mice with different MIP-1α backgrounds. Each group contained 10–15 mice. (c and d) Mean (±SEM) time to fall off the rotorod. Both Hexb^-/-MIP-1α^+/- and Hexb^-/-MIP-1α^-/- mice had significantly better (*) performances at all time points tested. The comparison was made only among the littermates. At all time points in c, n = 4 Hexb^-/-MIP-1α^+/+ mice and 4 Hexb^-/-MIP-1α^+/- mice. At all time points in d, n = 3 Hexb^-/-MIP-1α^+/+ mice and 3 Hexb^-/-MIP-1α^-/- mice. The righting reflex was tested at 17 (e) and 19 (f) weeks of age; n = 4 in each group and time point. Hexb^-/-MIP-1α^-/- mice had a significantly improved (*) righting reflex compared with other groups. All Hexb^-/-MIP-1α^+/+ mice were dead by 19 weeks old.