Mortality risk by age at study entry across DOPPS regions. Cross section of participants in DOPPS III (2005 through 2007; n = 8161); number of deaths n = 1337. Reference (Ref) group: patients <45 years of age. Model adjusted for sex, race, body mass index, duration of ESRD, 14 summary comorbid conditions listed in Table 1 (dementia was included in the neurologic diseases), stratified by country, and accounted for facility clustering effect. Mean age in category: <45 years = 36, 45 to 75 years = 62, ≥75 years = 80. Europe includes United Kingdom, France, Germany, Italy, Spain, Belgium, and Sweden; North America includes United States and Canada; ANZ represents Australia and New Zealand; HR, Hazard Ration; CI, confidence interval.