Table 1.
Patient characteristics | Europe |
Australia and New Zealand |
Japan |
North America |
||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
<45 years |
45 to 74 years |
≥75 years |
<45 years |
45 to 74 years |
≥75 years |
<45 years |
45 to 74 years |
≥75 years |
<45 years |
45 to 74 years |
≥75 years |
|||||||||||||
mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | mean or % | 95% CI | |
Male (%) | 60.1 | (54.6–65.5) | 58.8 | (56.6–61.1) | 54.2 | (50.8–57.6) | 43.8 | (30.3–57.4) | 54.3 | (48.8–59.9) | 73.1 | (64.5–81.6) | 71.1 | (63.4–78.8) | 61.7 | (58.9–64.6) | 53.1 | (47.2–59) | 59.4 | (53.1–65.7) | 56.5 | (53.5–59.5) | 53.1 | (48.3–57.9) |
Black race (%) | 4.3 | (1.3–7.4) | 1.9 | (1.2–2.6) | 0.7 | (0.2–1.3) | 2.1 | (0–6.1) | 0.2 | (0–0.7) | 1.7 | (0–4) | 0 | 0 | 0 | 33.6 | (27.9–39.3) | 29.1 | (26.5–31.7) | 13 | (9.9–16) | |||
Duration of ESRD (year) (mean) | 6.8 | (5.8–7.8) | 5.1 | (4.8–5.4) | 3.7 | (3.4–3.9) | 6.5 | (4.5–8.6) | 4.9 | (4.4–5.4) | 4.5 | (3.9–5.2) | 7.7 | (6.7–8.7) | 9.2 | (8.8–9.7) | 5.7 | (5–6.3) | 5.1 | (4.5–5.8) | 4 | (3.8–4.3) | 2.9 | (2.7–3.2) |
BMI (mean) | 23.8 | (23.1–24.5) | 25.6 | (25.4–25.8) | 24.3 | (24–24.6) | 27.8 | (25.6–30) | 27.7 | (27–28.5) | 25.5 | (24.5–26.4) | 21.4 | (20.8–22.1) | 21.1 | (20.9–21.3) | 20.3 | (20–20.6) | 27.9 | (26.8–29) | 27.9 | (27.5–28.3) | 25 | (24.4–25.5) |
Dry weight (kg) (mean) | 68.2 | (65.4–71) | 71.7 | (70.9–72.4) | 65.8 | (64.9–66.7) | 77.7 | (70.4–85.1) | 77 | (74.8–79.3) | 68.3 | (65.4–71.2) | 58 | (55.6–60.4) | 54.4 | (53.8–55.1) | 48.3 | (47.3–49.3) | 79.3 | (76.1–82.6) | 80.4 | (79–81.8) | 67.7 | (66.2–69.3) |
Unable to walk without assistance (%) | 8.1 | (5.2–11) | 20.7 | (18.8–22.6) | 35 | (31.7–38.3) | 11.5 | (2.8–20.1) | 23.4 | (18.6–28.2) | 39.9 | (30.3–49.5) | 4.5 | (1.3–7.7) | 10.7 | (8.9–12.5) | 32 | (26.6–37.4) | 11.8 | (7.8–15.7) | 30.7 | (27.9–33.6) | 47.1 | (42.2–52) |
Comorbid conditions (%) | ||||||||||||||||||||||||
coronary artery disease | 12.4 | (9–15.9) | 41 | (38.8–43.3) | 46 | (42.6–49.3) | 15.8 | (5.5–26) | 56.2 | (50.7–61.7) | 55 | (45.3–64.6) | 11.6 | (6.1–17.1) | 27.5 | (24.8–30.1) | 38.5 | (32.8–44.2) | 25.7 | (20.1–31.3) | 50.9 | (47.8–53.9) | 63.3 | (58.6–67.9) |
cancer other than skin | 6.6 | (4–9.3) | 14.2 | (12.6–15.8) | 18.9 | (16.3–21.4) | 3.7 | (0–8.8) | 13 | (9.3–16.7) | 22.6 | (14.6–30.5) | 0.6 | (0–1.8) | 9 | (7.3–10.6) | 11.4 | (7.6–15.2) | 3.5 | (0.6–6.5) | 12.2 | (10.2–14.2) | 20.8 | (16.8–24.9) |
other cardiovascular disease | 20.1 | (15.8–24.4) | 40.1 | (37.9–42.3) | 60.2 | (56.9–63.5) | 11.4 | (2.8–20.1) | 35.1 | (29.8–40.4) | 46.6 | (36.9–56.3) | 17.7 | (10.9–24.6) | 31.7 | (28.9–34.5) | 46.1 | (40.2–52) | 16.6 | (11.9–21.3) | 34.2 | (31.3–37.1) | 51.9 | (47.1–56.7) |
cerebrovascular disease | 7.6 | (4.9–10.4) | 18 | (16.2–19.7) | 25.6 | (22.6–28.6) | 6.8 | (0.3–13.3) | 19.9 | (15.5–24.3) | 29.8 | (21–38.6) | 1.6 | (0–3.3) | 12.8 | (10.8–14.8) | 18.5 | (14.2–22.7) | 4.2 | (1.9–6.5) | 19.4 | (17–21.7) | 22.9 | (18.7–27.1) |
congestive heart failure | 23.9 | (19.1–28.7) | 41.2 | (38.9–43.4) | 47.3 | (44–50.7) | 31.4 | (18.3–44.4) | 46 | (40.5–51.6) | 49.2 | (39.5–58.9) | 13.2 | (7.3–19.2) | 22.6 | (20.2–25.1) | 36 | (30.4–41.6) | 24.1 | (19–29.1) | 47.8 | (44.7–50.8) | 58 | (53.2–62.7) |
diabetes | 16.3 | (12.2–20.4) | 33.5 | (31.3–35.7) | 29.6 | (26.5–32.6) | 34.4 | (21.1–47.7) | 46.4 | (40.8–52) | 40 | (30.4–49.6) | 16.7 | (10.5–22.9) | 32.8 | (30–35.6) | 35.2 | (29.5–40.9) | 24 | (18.8–29.1) | 60.1 | (57.1–63.2) | 48.8 | (44–53.6) |
GI bleeding in prior 12 months | 1.4 | (0.3–2.5) | 4.7 | (3.8–5.5) | 6 | (4.4–7.6) | 5 | (0–10.6) | 3.4 | (1.5–5.4) | 11.8 | (5.6–18) | 3.4 | (0.4–6.4) | 3.9 | (2.8–5) | 4.4 | (2.2–6.7) | 3.4 | (1.4–5.5) | 6.1 | (4.6–7.6) | 8.9 | (5.9–11.8) |
HIV/AIDS | 1.5 | (0.2–2.8) | 0.4 | (0.1–0.8) | 0.1 | (0–0.2) | 0 | 0.3 | (0–0.9) | 0 | 0.7 | (0–1.8) | 0.4 | (0.1–0.7) | 0.4 | (0–0.9) | 3.1 | (1.1–5.1) | 0.9 | (0.3–1.4) | 0 | |||
hypertension | 73.5 | (68.4–78.6) | 79.1 | (77.2–81.1) | 79 | (76.1–81.9) | 70.8 | (58.8–82.9) | 85 | (81–88.9) | 85.2 | (78.3–92) | 58.8 | (50.2–67.4) | 70.2 | (67.5–72.9) | 78.2 | (73.5–82.9) | 86.6 | (81.8–91.3) | 87.5 | (85.4–89.6) | 87.3 | (83.9–90.7) |
lung disease | 3.4 | (1.6–5.3) | 13 | (11.5–14.5) | 16.4 | (14–18.8) | 0 | 19.5 | (15–24.1) | 25.8 | (17–34.6) | 1.1 | (0–2.7) | 2.4 | (1.4–3.4) | 4.3 | (2–6.6) | 5.9 | (3.2–8.6) | 19.1 | (16.8–21.4) | 24.5 | (20.5–28.6) | |
neurological disease | 9.8 | (6.8–12.9) | 10.3 | (8.9–11.6) | 14 | (11.8–16.3) | 13.1 | (4.5–21.7) | 9 | (5.9–12.2) | 12.2 | (6.1–18.3) | 4 | (1.2–6.8) | 6.3 | (4.9–7.6) | 25 | (19.9–30.1) | 14.8 | (10.7–18.8) | 11.8 | (9.8–13.8) | 15.1 | (11.8–18.5) |
dementia | 0.5 | (0–1.1) | 2.1 | (1.5–2.8) | 3.6 | (2.4–4.9) | 0 | 1.4 | (0.2–2.7) | 7.4 | (2.4–12.4) | 0 | 2 | (1.2–2.8) | 22 | (17.1–26.8) | 0.6 | (0–1.5) | 2 | (1.2–2.7) | 7.5 | (5–10) | ||
other psychiatric disorder | 10.4 | (7.2–13.7) | 11.6 | (10.1–13.1) | 9.7 | (7.6–11.8) | 15.4 | (5.4–25.5) | 18.9 | (14.3–23.4) | 12.3 | (5.9–18.7) | 1.9 | (0–3.9) | 3.8 | (2.7–4.9) | 1.9 | (0.4–3.3) | 27.4 | (21.9–33) | 20.2 | (17.8–22.6) | 12.9 | (9.5–16.3) |
peripheral vascular disease | 9.7 | (6.6–12.9) | 32.2 | (30.1–34.3) | 35.7 | (32.5–39) | 11.7 | (2.7–20.7) | 33.8 | (28.6–39.1) | 49.2 | (39.5–58.9) | 4.7 | (0.4–9.1) | 17.7 | (15.4–20) | 21.6 | (17–26.3) | 11.7 | (7.9–15.5) | 35.9 | (33–38.9) | 35.5 | (30.8–40.2) |
recurrent cellulitis, gangrene | 6.1 | (2.8–9.4) | 10.9 | (9.5–12.3) | 7 | (5.2–8.8) | 6.3 | (0–13.5) | 14.1 | (10.1–18) | 13.7 | (6.9–20.5) | 1.4 | (0–3.4) | 3.8 | (2.6–5) | 4.9 | (2.4–7.4) | 7.6 | (4.3–11) | 12.9 | (10.7–15) | 7.3 | (4.6–9.9) |
Cross section of hemodialysis patients in DOPPS III (2005 through 2007) (n = 8161). Bold numbers represent P < 0.05 compared to the elderly group (≥75 years) within each region. Europe includes United Kingdom, France, Germany, Italy, Spain, Belgium, and Sweden; North America includes United States and Canada. Abbreviation: 95% CI = 95% confidence interval; DOPPS, Dialysis Outcomes and Practice Patterns Study; BMI, body mass index; GI, gastrointestinal.