Table 1. Immunophenotypic analysis: Distribution of lineage-affiliated cells in TEL-AML1-positive and -negative fractions.
| Distribution among lineage markers, %
|
|||||
|---|---|---|---|---|---|
| BM cells | B220 | CD3 | TER-119 | Gr-1/Mac-1 | Lineage-negative |
| TEL-AML1-GFP-negative | 29.4 ± 4.1 | 5.0 ± 1.1 | 4.2 ± 0.8 | 61.0 ± 4.1 | 1.8 ± 0.4 |
| TEL-AML1-GFP-positive | 9.3 ± 3.1 | 2.8 ± 1.0 | 19.4 ± 2.1 | 56.9 ± 6.4 | 12.1 ± 4.1 |
| Vector-only GFP-positive | 27.3 ± 5.6 | 5.8 ± 1.1 | 4.0 ± 1.2 | 60.2 ± 5.6 | 1.7 ± 0.4 |
BM cells from TEL-AML1 or GFP-only control mice were analyzed for lineage markers (B cell B220; T cell CD3; erythroid cells TER-119; granulomonocytic cells Gr-1/Mac-1). Data are presented as the mean ± SD of three mice analyzed.