Figure 5.

The production of T-cell polarizing cytokines by DC upon stimulation with LOS modified NOMV. Human monocyte-derived DC were stimulated with 1 μg ml⁻¹ LOS modified NOMV for 18–24 h. Supernatants were collected and then analysed for the presence T-cell polarizing cytokines IL-10 (A), IL-23 (B), IL-12p70 (C) and PGE₂ (D) by ELISA. A summary of data is shown for eight human donors. Data are expressed as the mean and standard error of the mean. Statistical significance was tested using a paired t-test.