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Lack of thrombosis and evidence of cellular rejection of GTKO/CD55-CD59-HT NICC xenografts 1 month after transplant. Baboon liver sections were stained with hematoxylin and eosin (A), Martius Scarlet Blue (B), or antibodies for chromogranin A (C), insulin (D), glucagon (E), somatostatin (F), CD3 (G) or CD20 (H). All images ×20 magnification. GTKO/CD55-CD59-HT, GTKO pigs expressing human CD55, CD59 and α1,2-fucosyltransferase (H-transferase, HT); NICC, neonatal islet cell clusters.
