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GTKO/CD55-CD59-HT NICC trigger significantly less complement activation (A) and thrombin generation (B) than WT NICC when incubated in vitro with baboon platelet-poor plasma. Data are shown as mean ± SD of 10 independent experiments. * p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. GTKO/CD55-CD59-HT, GTKO pigs expressing human CD55, CD59 and α1,2-fucosyltransferase (H-transferase, HT); NICC, neonatal islet cell clusters.
