Table 1.

Summary data for baboon transplants performed including the NICC yields from WT and GTKO/CD55-CD59-HT piglet pancreases used for transplantation

Baboon	Weight (kg)	Donors	Total no. of NICC	NICC/g pancreas	Total no. of IEQ	IEQ/g pancreas	NICC/kg	IEQ/kg	Total no. of NICC/mm3 liver	rhAT (U) total dose
WT1	21	WT	547 500	39 360	185 432	13 330	26 071	8830	0.0276	10 500
WT2	22	WT	547 500	39 360	185 432	13 330	24 886	8429	0.0260	None
WT3	24	WT	508 750	24 261	156 396	7461	21 198	6517	0.0231	12 000
WT4	23	WT	508 750	24 261	156 396	7461	22 120	6800	0.0241	None
		Mean	528 125	31 811	170 914	10 396	23 569	7644	0.0252
		SD	22 372	8717	16 764	3388	2289	1156	0.0020
GM1	12	GTKO/CD55-CD59-HT	491 505	22 525	135 654	6217	40 959	11 305	0.0223	None
GM2	12	GTKO/CD55-CD59-HT	445 500	25 766	111 927	6474	37 125	9327	0.0222	None
GM3	10	GTKO/CD55-CD59-HT	318 750	12 340	53 875	2086	31 875	5388	0.0177	None
GM4	10	GTKO/CD55-CD59-HT	805 000	23 802	224 124	6627	80 500	22 412	0.0447	None
GM5	8	GTKO/CD55-CD59-HT	783 133	27 459	328 103	11 504	97 892	41 013	0.0502	None
		Mean	568 778	22 378	170 737	6582	57 670	17 889	0.0314
		SD	215 309	5918	107 192	3339	29 605	14 389	0.0148

GM, genetically modified; IEQ, islet equivalent; NICC, neonatal islet cell clusters; rhAT, recombinant human anti-thrombin; SD, standard deviation.