Fig. 5.

The percentage of spikes contained within bursts decreased with high doses of MK801. The percentage of spikes contained within bursts was calculated for each neuron during a 30-min baseline period and during four sequential 30-min postinjection periods. Data for all groups and response types is summarized by plotting the linear regression coefficients. Numbers under each bar indicate the postinjection time period as follows: lanes 1, 0–30 min; lanes 2, 30–60 min; lanes 3, 60–90 min; and lanes 4, 90–120 min. Higher doses of MK801 caused a significant decrease in the percentage of neurons in bursts, regardless of the response type. Asterisks indicate significant difference from a regression coefficient of 1.0, which indicates no change from baseline.