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. 2012 Feb 15;2012(2):CD002212. doi: 10.1002/14651858.CD002212.pub2

for the main comparison.

Evidence‐based standardised nursing procedure to improve care of patients at risk of developing hospital‐acquired pressure ulcers (HAPUs)
Patient or population: nurses, and patients admitted with a Braden score less than or equal to 18 (i.e. at risk of developing HAPUs)
Settings: one hospital
Intervention: evidence‐based standardised nursing procedure
Comparison: N/A
Outcomes Change in level effect (mean rate per quarter) (95% CI)* No of participants 
 (studies) Quality of the evidence 
 (GRADE) Comments
HAPU rate At 3 months: 0.7% (95% CI ‐1.7 to 3.3), P = 0.465) One hospital 
 (1) ⊕⊝⊝⊝ 
 very low quality* Before the intervention there was a statistically significant (P = 0.046) decrease in mean HAPU rate by 1.1% per quarter
Given the small percentages post intervention it was not possible to extrapolate effects beyond 3 months
* We downgraded the evidence on the basis of imprecision and the downward trend in HAPU rate found already in the pre‐intervention period.
GRADE Working Group grades of evidence 
 High quality: Further research is very unlikely to change our confidence in the estimate of effect. 
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. 
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. 
 Very low quality: We are very uncertain about the estimate.