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. Author manuscript; available in PMC: 2014 Oct 21.
Published in final edited form as: Cochrane Database Syst Rev. 2012 May 16;5:CD001087. doi: 10.1002/14651858.CD001087.pub4
Outcomes Illustrative comparative risks* (95% CI)
Relative effect (95% CI) No of Participants (studies) Quality of the evidence (GRADE) Comments
Assumed risk Corresponding risk

STANDARD CARE CRISIS INTERVENTION
Global state
Global Assessment Scale (GAS) Follow-up: 12 months
The mean global state in the control groups was 64.4 The mean global state in the intervention groups was 5.7 higher (0.26 lower to 11.66 higher) 142 (1 study) ⊕ ⊕ ⊕ ○ moderate1,2 Outcome measure favours crisis intervention over standard care, although not to a significant extent

Mental state - general Brief Psychiatric Rating Scale (BPRS) Follow-up: 3 months The mean mental state - general in the control groups was 43.5 The mean mental state - general in the intervention groups was 4.03 lower (8.18 lower to 0.12 higher) 248 (2 studies) ⊕ ⊕ ○ ○ low3,4 Outcome measure favours crisis intervention, although not to a significant extent

Patient Satisfaction Client Satisfaction Questionnaire (CSQ-8) Follow-up: 20 months The mean patient satisfaction in the control groups was 22.0 The mean patient satisfaction in the intervention groups was 5.4 higher (3.91 to 6.89 higher) 137 (1 study) ⊕ ⊕ ⊕ ○ moderate1,2 Outcome favours crisis intervention to a significant extent

Quality of Life Manchester Short Assessment (MANSA) Follow-up: 6 months The mean quality of life in the control groups was 41.7 The mean quality of life in the intervention groups was 1.5 lower (5.15 lower to 2.15 higher) 226 (1 study) ⊕ ⊕ ○ ○ low3,4 Outcome favours standard care although not to a significant extent

Burden on family Numbers of families stating that overall burden is great Follow-up: 6 months 583 per 1000 198 per 1000 (117 to 344) RR 0.34 (0.2 to 0.59) 120 (1 study) ⊕ ⊕ ○ ○ low2,4 Outcome significantly favours crisis intervention

Hospital use Repeat admissions excluding index admission Follow-up: 6 months 758 per 1000 470 per 1000 (387 to 576) RR 0.62 (0.51 to 0.76) 258 (1 study) ⊕ ⊕ ⊕ ⊕ high Outcome significantly favours crisis intervention
*

The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio;

GRADE Working Group grades of evidence

High quality: Further research is very unlikely to change our confidence in the estimate of effect.

Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.

Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.

Very low quality: We are very uncertain about the estimate.

1

Details of randomisation not described.

2

Blinding not described

3

Raters not blinded

4

Loss of some participants not described