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. 2014 Oct 21;4:290. doi: 10.3389/fonc.2014.00290

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Copyright © 2014 Rana, Cyr, Chen, Kim, Moures, Yung, Lei, Collins, Suy, Dritschilo, Lynch and Collins.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IPSS-irritative subscores over the 36 months of follow-up stratified by baseline LUTS. (A) Mean IPSS-irritative score for all patients. (B) Mean values of patients with a mild baseline LUTS (IPSS < 8, n = 102). (C) Mean values of patients with a moderate to severe baseline LUTS (IPSS ≥ 8, n = 102). Changes in scores that are statistically significant different from baseline are marked with an asterisk (*). Thresholds for clinically significant changes in scores (1/2 standard deviation above and below the baseline) are marked with dashed lines. IPSS-irritative scores range from 0 to 15 with lower values representing a more favorable outcome.