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Seed profiles of representative mild and severe Parkinson’s disease (PD) patients. (A) Representative mild PD patient’s speed profiles. (B) Severe PD patient’s speed profiles. Notice the “jitter” in these profiles particularly on the spontaneous retraction, adding to the overall variability patterns. (C) Sample trajectories and speed profiles of another severe PD patient with problems initiating motions and resting tremor as well (both epochs circled).
